All matchups
Buffalo Bills @ Houston Texans
Sunday, September 13 at 1:00 PM EDT
BUF
-1.5
-120
Total
44.5
HOU
+1.5
+100
The Read
Buffalo Bills open a 1.5-point favorite over Houston Texans — about 55% implied to win outright. The 44.5 total prices it near 23–22.
Buffalo Bills went 12–5 in 2025 — #6 of 32 by point differential (+6.8/g).
Houston Texans went 12–5 in 2025 — #5 of 32 by point differential (+6.4/g).
2025 team profiles
Buffalo Bills
2025 record12-5Point diff / game+6.8Pythag wins (rank)11.2 (#6)2026 SOS rank#8
Houston Texans
2025 record12-5Point diff / game+6.4Pythag wins (rank)11.5 (#5)2026 SOS rank#26