All matchups
Los Angeles Rams @ Arizona Cardinals
Sunday, November 15 at 4:05 PM EST
LA
-10.5
-470
Total
47.5
ARI
+10.5
+360
The Read
Los Angeles Rams open a 10.5-point favorite over Arizona Cardinals — about 82% implied to win outright. The 47.5 total prices it near 29–19.
Los Angeles Rams went 12–5 in 2025 — #3 of 32 by point differential (+10.1/g).
Arizona Cardinals went 3–14 in 2025 — #29 of 32 by point differential (-7.8/g), and were 2.4 wins unlucky versus their margin.
Arizona Cardinals face one of the NFL's toughest 2026 schedules (strength of schedule #3).
2025 team profiles
Los Angeles Rams
2025 record12-5Point diff / game+10.1Pythag wins (rank)12.3 (#3)2026 SOS rank#13
Arizona Cardinals
2025 record3-14Point diff / game-7.8Pythag wins (rank)5.4 (#29)2026 SOS rank#3